High Prevalence of Panton-Valentine Leukocidin Among Methicillin-SensitiveStaphylococcus aureusColonization Isolates in Rural Iowa

Panton-valentine Leukocidin Expression in Community Associated Methicillin Resistant Staphylococcus Aureus Isolates from Rural Alaska

AND SPECIFIC AIMS Incidence of infection by Methicillin resistant Staphyloccocus aureus (MRSA) has historically been attributed to nosocomial sources, but there is currently an increasing trend towards community acquired infection not associated with hospital settings. Community-associated MRSA (CA-MRSA) is most often associated with skin and soft tissue infections rather than invasive disease....

Prevalence of Panton-Valentine leukocidin genes among carriage and invasive Staphylococcus aureus isolates in Malaysia.

Molecular characterization of Panton-Valentine leukocidin-positive community-acquired methicillin-resistant Staphylococcus aureus isolates in Egypt.

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) expressing Panton-Valentine leukocidin (PVL) have been characterized worldwide, but it has not been done in Egypt. In this study, we analyzed the molecular characteristics of PVL+CA-MRSA in Egypt, compared their genetic patterns with that of PVL+ methicillin-susceptible S. aureus and PVL+CA-MRSA from different countries, a...

Panton-Valentine Leukocidin Genes in Staphylococcus aureus

To the Editor: The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue infections, particularly furuncu...

Expression of Panton-Valentine Leukocidin mRNA among Staphylococcus aureus Isolates Associates with Specific Clinical Presentations

Panton-Valentine leukocidin (PVL; gene designation lukF/S-PV) is likely an important virulence factor for Staphylococcus aureus (S. aureus), as qualitative expression of the protein correlates with severity for specific clinical presentations, including skin and soft tissue infections (SSTIs). Development of genetic approaches for risk-assessment of patients with S. aureus infections may prove ...